David N. Arnosti
Professor
  • B.A. 1982, Lawrence University, Appleton, WI
  • Ph.D. 1989, University of California, Berkeley
  • Postdoctoral Researcher, 1990-92, University of Zurich, Switzerland 1993-96, UC San Diego.

arnosti@msu.edu
413 Biochemistry Building
Michigan State University
East Lansing, MI 48824-1319
Office: 517-432-5504
Lab: 517-355-1606

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David N. Arnosti Recent Publications


Martinez, C. A. and D. N. Arnosti. Spreading of corepressor linked to action of long-range repressor Hairy. Molecular and Cellular Biology, in press.

Mani-Telang P, Sutrias-Grau M, Williams G, Arnosti DN. (2007) Role of NAD binding and catalytic residues in the C-terminal binding protein corepressor. FEBS Lett. 581:5241-6. See abstract

Halfon, M.S., Arnosti, D.N. 2007. New Tools, Resources for Gene Regulatory Analysis in Drosophila. [Epub ahead of print] e1 Fly 2007; Vol. 1 Issue 2. See abstract

Zakir Ullah, Martin Buckley, David N. Arnosti, and R. William Henry. (2007) Retinoblastoma Protein Regulation by the COP9 Signalosome. Mol Biol Cell, in press. (Published online ahead of print January 24, 2007.) See abstract

Mani-Telang P, Arnosti DN. (2006) Developmental expression and phylogenetic conservation of alternatively spliced forms of the C-terminal binding protein corepressor Dev Genes Evol. 2006 Nov 21; [Epub ahead of print]. See abstract

P Struffi and D. N. Arnosti. (2005) Functional interaction between the Drosophila knirps short-range transcriptional repressor and Rpd3 histone deacetylase. J. Biol. Chem. Dec 9;280(49):40757-65. Epub 2005 Sep 26. See pdf

D. N. Arnosti and M. M. Kulkarni.( 2005) Transcriptional Enhancers: Intelligent Enhanceosomes or Flexible Billboards? J. Cell. Biochem. 94: 890-898. See pdf

S. A. Keller, Z. Ullah, M. S. Buckley, R. W. Henry and D. N. Arnosti. (2005) Distinct developmental expression of Drosophila retinoblastoma factors. Mechanisms of Development, Gene Expression Patterns 5: 411-421. See pdf

M. M. Kulkarni and D. N. Arnosti. (2005)Cis-regulatory logic of short-range transcriptional repression in Drosophila. Mol. Cell. Biol. 25:3411-3420. See pdf

M. Sutrias-Grau and D. N. Arnosti. (2004) CtBP contributes quantitatively to Knirps repression activity in an NAD binding dependent manner. Molecular and Cellular Biology 245953-245966. See pdf

D. N. Arnosti. Multiple Mechanisms of Transcriptional Repression in Eukaryotes. In Handbook of Experimental Pharmacology, J. Kaufmann, S. J. Triezenberg and M. Gossen eds., Springer (Berlin) 2004. See pdf

P. Struffi, M. Corado, M.M. Kulkarni, and D. N. Arnosti. (2004) Quantitative contributions of CtBP-dependent and -independent repression activities of Knirps. Development, 1312419-1312429. See pdf

M.M. Kulkarni and D.N. Arnosti. (2003) Information display by transcriptional enhancers. Development 130:6569-6575. See pdf

J.R. Ryu and D.N. Arnosti. (2003) Functional similarity of Knirps CtBP-dependent and CtBP-independent transcriptional repressor activities. Nuc. Acids Res., 31: 4654-4662. See pdf

D. N. Arnosti (2003)Analysis and function of transcriptional regulatory elements: insights from Drosophila. Annu. Rev. Entomol. 48: 579 - 602. See pdf

D.N. Arnosti (2002)Design and Function of Transcriptional Switches in Drosophila, Insect Biochemistry and Molecular Biology, 32, 1257-1273. See pdf

J.R. Ryu, L.K. Olson, and D.N. Arnosti (2001) Cell-type specificity of short-range transcriptional repressors, Proc. Natl. Acad. Sci. USA, 98 12960-65. See pdf

B. Strunk, P. Struffi, K. Wright, B. Pabst, J. Thomas, L. Qin, and D.N. Arnosti (2001)Role of CtBP in transcriptional repression by the Drosophila giant protein. Developmental Biology, 239 (2) 229-40. See pdf

Keller, S.A., Mao, Y.M., Struffi, P., Margulies, C. and D. N. Arnosti dCtBP dependent and independent repression activities of the Drosophila Knirps protein" (2000) Mol. Cell. Biol. 207247-7258.See pdf

Hewitt, G.F., Strunk, B.S., Priputin, T., Wang, X.-D., Amey, R., Pabst, B.A., Kosman, D., Reinitz, J., and Arnosti, D.N. (1999)Transcriptional repression by the Drosophila Giant protein cis element positioning provides an alternative means of interpreting an effector gradient", Development 126 (6) 1201-1210. See pdf

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