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David Arnosti
David N. Arnosti
Professor
  • B.A. 1982, Lawrence University, Appleton, WI
  • Ph.D. 1989, University of California, Berkeley
  • Postdoctoral Researcher, 1990-92, University of Zurich, Switzerland 1993-96, UC San Diego.

arnosti@msu.edu
413 Biochemistry Building
Michigan State University
East Lansing, MI 48824-1319
Office: 517-432-5504
Lab: 517-355-1606

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Recent Publications

*Fakhouri WD, *Ay A, Sayal R, Dresch J, Dayringer E, Chiu C, Arnosti DN. 2009. Deciphering a transcriptional regulatory code: modeling short-range repression in the Drosophila embryo. Molecular Systems Biology. In press. (* - equal contribution)  msb2009dataset

Payankaulam and Arnosti. (2009) Groucho corepressor functions as a cofactor for the Knirps short-range transcriptional repressor. Proc Natl Acad Sci USA (PNAS). 13;106(41):17314-9. See pdf

Ay A, Fakhouri WD, Chiu C, Arnosti DN. (2008) Image Processing and Analysis for Quantifying Gene Expression from Early Drosophila Embryos. Tissue Eng Part A. 14(9):1517-26. See abstract

Payankaulam S, Arnosti DN. (2008) Gene Regulation: Boundaries within Limits. Curr Biol. 18(15):R653-5. See pdf

Martinez, C. A. and D. N. Arnosti. (2008) Spreading of corepressor linked to action of long-range repressor Hairy. Mol Cell Biol. 28(8):2792-802. See pdf

Mani-Telang P, Sutrias-Grau M, Williams G, Arnosti DN. (2007) Role of NAD binding and catalytic residues in the C-terminal binding protein corepressor. FEBS Lett. 581:5241-6. See abstract

Halfon, M.S., Arnosti, D.N. 2007. New Tools, Resources for Gene Regulatory Analysis in Drosophila. [Epub ahead of print] e1 Fly 2007; Vol. 1 Issue 2. See abstract

Zakir Ullah, Martin Buckley, David N. Arnosti, and R. William Henry. (2007) Retinoblastoma Protein Regulation by the COP9 Signalosome. Mol Biol Cell, in press. (Published online ahead of print January 24, 2007.) See abstract

Mani-Telang P, Arnosti DN. (2006) Developmental expression and phylogenetic conservation of alternatively spliced forms of the C-terminal binding protein corepressor Dev Genes Evol. 2006 Nov 21; [Epub ahead of print]. See abstract

Struffi P, Arnosti DN. (2005) Functional interaction between the Drosophila knirps short-range transcriptional repressor and Rpd3 histone deacetylase. J. Biol. Chem. Dec 9;280(49):40757-65. Epub 2005 Sep 26. See pdf.

D. N. Arnosti and M. M. Kulkarni.( 2005) Transcriptional Enhancers: Intelligent Enhanceosomes or Flexible Billboards? J. Cell. Biochem. 94: 890-898. See pdf

S. A. Keller, Z. Ullah, M. S. Buckley, R. W. Henry and D. N. Arnosti. (2005)Distinct developmental expression of Drosophila retinoblastoma factors. Mechanisms of Development, Gene Expression Patterns 5: 411-421. See pdf

M. M. Kulkarni and D. N. Arnosti. 2005. Cis-regulatory logic of short-range transcriptional repression in Drosophila. Mol. Cell Biol 9: 3411-20. See pdf

M. Sutrias-Grau and D. N. Arnosti. (2004) CtBP contributes quantitatively to Knirps repression activity in an NAD binding dependent manner. Molecular and Cellular Biology 245953-245966. See pdf.

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