Kathleen A. Gallo
Professor
  • Ph.D. 1992, Harvard University
  • Postdoctoral Researcher 1992-1995, Genentech

gallok@msu.edu
4180 Biomedical & Physical Sci
Michigan State University
East Lansing, MI 48824-1319
Office: 517-355-6475 ext 1159
Lab: 517-355-6475 ext 1378

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Kathleen Gallo Recent Publications

Gallo KA. (2006) Targeting HSP90 to halt neurodegeneration. Chem Biol. 13(2):115-6. Link to reprint

Mata IF, Wedemeyer WJ, Farrer MJ, Taylor JP, Gallo KA. (2006) LRRK2 in Parkinson's disease: protein domains and functional insights. Trends Neurosci. 29(5):286-93. Review. Link to reprint

Schachter KA, Du Y, Lin A, Gallo KA. (2006) Dynamic positive feedback phosphorylation of mixed lineage kinase 3 by JNK reversibly regulates its distribution to Triton-soluble domains. J Biol Chem. 281(28):19134-44. Link to reprint

Du Y, Bock BC, Schachter KA, Chao M, Gallo KA. (2005) Cdc42 induces activation loop phosphorylation and membrane targeting of MLK3. J Biol Chem. Dec 30;280(52):42984-93. Link to reprint

Zhang H, Wu W, Du Y, Santos SJ, Conrad SE, Watson JT, Grammatikakis N, Gallo KA. (2004) Hsp90/p50cdc37 is required for mixed-lineage kinase (MLK) 3 signaling. J Biol Chem. May 7;279(19):19457-63. Epub 2004 Mar 4. Link to reprint

Gallo, K. A. and Johnson, G.L. (2002) Signalling: Mixed-lineage kinase control of JNK and p38 MAPK pathways. Nature Reviews Molecular Cell Biology 3: 663-72. Link to reprint

Vacratsis, P. O., Phinney, B. S., Gage, D. A., and Gallo, K. A. (2002) Identification of in vivo phosphorylation sites of MLK3 by mass spectrometry and phosphopeptide mapping. Biochemistry 41, 5613-24. Link to reprint

Parameswaran, N., C.S. Hall, B.C. Bock, H.V. Sparks, K.A. Gallo, and W.S. Spielman (2002) Mixed lineage kinase 3 inhibits phorbol myristoyl acetate-induced DNA synthesis but not osteopontin expression in rat mesangial cells. Molecular and Cellular Biochemistry 241: 37-43.

Parameswaran, N., C.S. Hall, B.C. Bock, H.V. Sparks, K.A. Gallo, and W.S. Spielman (2002) Mixed lineage kinase 3 inhibits platelet-derived growth factor-stimulated DNA synthesis and matrix mRNA expression in mesangial cells. Cellular Physiology and Biochemistry 12: 325-34.

Zhang, H. and K. A. Gallo (2001) Autoinhibition of mixed lineage kinase 3 through its Src homology 3 domain. J. Biol. Chem. 276: 45598-603 Link to reprint

Vacratsis, P. O. and K. A. Gallo (2000) Zipper-mediated oligomerization of the mixed lineage kinase SPRK/MLK-3 is not required for its activation by the GTPase Cdc 42 but is necessary for its activation of the JNK pathway. J. Biol. Chem.: 275, 27893-900. Link to reprint

Bock, B. C., P. O. Vacratsis, E. Qamirani and K. A. Gallo (2000) Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation. J. Biol. Chem. 275: 14231-41 Link to reprint

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